My daughter will be attending school in Venice from Oct.-Dec. My wife wants to visit over Thanksgiving. Just wondering about weather & accomodations that time of year

You might try Hotel Campiello (www.hcampiello.it), Locando Gambero (www.locandaalgambero.com), or Hotel Bel Sito (www.hotelbelsito.info). The November averages for Venice are high temps in the 50s (Fahrenheit)with about 3 inches of rain. So pack warm rain gear!
Venice has a festival about the same time as our Thanksgiving, so you should have a lot of activities. Have fun!